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Fixed-Bed fermenter
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| Bioreactors
| Measurement
and Control technology Stirred Fermenter | Media autoclave |
From 1 ml fixed bed with scale-up possibility and from Laboratory to industrial scale. Immobilised, shear stress free culture of adherent cells, in serum or protein free medium. High cell density for long-term cultivation.
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mini-fixed-bed bioreactor 50mL |
fixed-bed bioreactor 5L | |||
- Double vessel: Fixed-bed with macro-porous material in the media-conditioning vessel, arranged centrally to save space
- Axial and special radial flow
- Temperature, pH and pO 2 control for media conditioning
- Shear stress free cultivation of cell-cultures in macro-porous material
- Use of serum or protein free media
- Batch-, fed-batch operation or optional continuous long-term cultivation with high level of sterility
- High cell density up to 108/ml
- Easy regeneration of the culture in cases of disruption
- Adjustment to different cell lines
- Saving expensive medium by low working volumes
- Saving work required through automated operation, without supervision
- only occasional replacement of medium bottle
